Tech Tuesday is an on-going series profiling the Forum’s Technology Pioneers. The Tech Pioneers are companies that have been recognized by the Forum for ground-breaking and innovative approaches in tackling some of the world’s most wicked problems. Each week we will be showcasing one of the 2013 Tech Pioneers. You can learn more about the Technology Pioneer Programme on the Forum’s website.

Ingenuity Systems: Finding hidden connections in the genome

Ingenuity Systems, founded by a group of former Stanford graduate students, develops pioneering software at the cutting edge of bioinformatics. The company’s Variant Analysis and IPA (Ingenuity Pathways Analysis) Web-based software are especially adept at identifying causal variants in the omic data that is emerging from whole genome sequencing and exome sequencing experiments. IPA is currently used by nearly all leading pharmaceutical companies. Its strong point is its ability to interactively analyse vast amounts of data from a variety of platforms and to visualize a set of results from different perspectives. Experimental data can also be compared with biological interactions in Ingenuity’s Knowledge database, which contains the records of millions of individually modelled relationships between proteins, genes, complexes, cells, tissues, metabolites, drugs and diseases.

Ingenuity’s iReport for Real-Time PCR (Polymerase Chain Reaction) provides a rapid and comprehensive understanding of pathways, processes and diseases relevant to gene expression. The company’s long-range focus is on enhancing the understanding of complex biological and chemical relationships within experimental data or models, as well as integrating biological information from multiple data types and sources. The tools that have emerged from Ingenuity’s research are designed to spot connections that will provide crucial insights needed to develop effective treatment for diseases previously classified as incurable. Experimental results can be compared with millions of biochemical interactions recorded in earlier experiments which are accessible through the Ingenuity Knowledge database.


Doug Bassett, Chief Scientific Officer & Chief Technology Officer
Location: CA, USA
Number of Employees: 120
Year Founded: 1998

Ingenuity Systems Inc.
1700 Seaport Boulevard
Redwood City, CA 94063

+1 650 381 5100