The foundation for a Latin American decade was at the core of the 2011 World Economic Forum on Latin America in Rio de Janeiro, Brazil. The meeting was held at an exceptional time in Latin American history, with most countries well positioned for economic growth, and most of them willing to engage actively on international issues. The region’s main challenge is to set realistic targets to be attained by the end of the decade, and to mobilize to reach them in a global landscape in deep transformation. To address this challenge, 750 top regional and global leaders from 45 countries convened around three thematic pillars: 1) Strengthening Regional and International Governance; 2) Enhancing Innovation and Productivity for Equitable Growth; and 3) Promoting Effective Partnerships for Sustainable Development.