Henry Markram

Professor, Ecole Polytechnique Fédérale de Lausanne (EPFL)

Henry Markram is a professor of neuroscience at the Swiss Federal Institute for Technology (EPFL). Co-founder of Frontiers Media, inait SA and the Open Brain Institute.

-Founder of the Brain Mind Institute (BMI.epfl.ch)
-Founder and Director of the Blue Brain Project (bluebrainproject.epfl.ch)
-Founder of the Human Brain Project (humanbrainproject.eu)
-Co-founder and Chairman of Frontiers (frontiersin.org)
-Co-founder and President, Frontiers Research Foundation (frontiersfoundation.org)
-Co-founder of the Frontiers Planet Prize (https://www.frontiersplanetprize.org)
-Co-Founder and President of the Open Brain Institute (openbraininstiture.org)
-Co-founder and Chairman of inait (inait.ai)

His work began in medicine and continued in neuroscience on the microstructure of the brain, how synapses learn, and how to build the brain digitally.

He generated over 450 papers, with ~150 on synaptic learning and the microarchitecture of the brain and ~300 on how to build biologically realistic digital copies of the brain, averaging ~86 citations/paper. His work has been cited ~55'000 times and he has an H-index ~95.

He discovered fundamental laws governing plasticity of synaptic connections (STDP, RSE, Rewiring, Common Neighbors, Legos, etc), characterized the microarchitecture of the neocortex, co-developed a theory of how the brain computes (Liquid/Reservoir Computing), brought algebraic topologists into neuroscience, and co-developed the Intense World Theory of Autism.

He pioneered simulation neuroscience in the Blue Brain project (BBP) focusing on the mouse brain since 2005 with a CHF 300 million Swiss Federal grant and in 2013 he united 80 institutes to win a €1 billion EU grant to focus on the human brain - the Human Brain Project (changed to EBRAINS).

Henry Markram completed the 20 year mission in the BBP to work out how to build digital copies of the brain and to simulate the brain on supercomputers and in the cloud.

https://www.epfl.ch/research/domains/bluebrain/blue-brains-scientific-milestones/

He co-founded the not-for-profit Open Brain Institute to open source all the data, models, algorithms and software (over 18 million lines of code) through Virtual Labs so that anyone can use, modify and build digital brain tissue.

The OBI launched in Jan 2025 with 43 ex-BBP team members to support the community to launch and run their own Virtual Lab to explore, build and simulate the brain and start performing "neuroscience at the speed of thought".

After completing his mission to build the brain he now focuses teaching digital brains to develop AGI in inait.ai.

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