Jenn leads the Genetics and clinical trials work at The African Academy of Sciences. She is responsible for the development and management of the (Human Heredity and Health in Africa (H3Africa) programme of activities and investments and also oversees the development of an Open Database for African Clinical Trials Capabilities and Sites. Prior to joining The AAS, Mabuka spent 16 years doing HIV-1 clinical research. Her research broadly focused on understanding host innate and immune factors that modulate HIV-1 transmission and pathogenesis. She investigated host immune responses in mother-to-child transmission of HIV-1 with a focus on breast milk transmission and explored antibody evolution in natural HIV-1 infection with the goal of informing antibody-based vaccine design. Mabuka holds a PhD from the University of Washington’s Department of Global Health and spent 3 years as a postdoctoral fellow with the Ragon Institute of MGH, MIT and Harvard and KwaZulu Natal Research Institute for TB and HIV (now Africa Health Research Institute- AHRI). She is currently a Clinical Associate Professor at the University of Washington in Seattle and a 2018 Aspen New Voices Fellow.